兔抗VAC14多克隆抗体

Background:

This gene encodes a scaffold protein that is a component of the PIKfyve protein kinase complex. This complex is responsible for the synthesis of phosphatidylinositol 3,5-bisphosphate, an important component of cellular membranes, from phosphatidylinositol 3-phosphate. Mice lacking a functional copy of this gene exhibit severe neurodegeneration. Mutations in the human gene have been identified in patients with a childhood onset progressive neurological disorder characterized by impaired movement, dystonia, and striatal abnormalities.

Applications:

ELISA, IHC

Name of antibody:

VAC14

Immunogen:

Fusion protein of human VAC14

Full name:

VAC14 component of PIKFYVE complex

Synonyms:

TRX; TAX1BP2; ArPIKfyve

SwissProt:

Q08AM6

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human breast cancer

IHC Recommend dilution:

100-200