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英文名称： SIRT1 Antigen (Recombinant Protein)
别 名： SIR2L1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
|
Fusion protein corresponding to C terminal 250 amino acids of human SIRT1 |
|
Full name: |
sirtuin 1 |
|
Synonyms: |
SIR2L1 |
|
Swissprot: |
Q96EB6 |
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Gene Accession: |
BC012499 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
