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Background: |
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. |
Applications: |
ELISA, IHC |
Name of antibody: |
VPS35 |
Immunogen: |
Fusion protein of human VPS35 |
Full name: |
VPS35 retromer complex component |
Synonyms: |
MEM3; PARK17 |
SwissProt: |
Q96QK1 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human esophagus cancer |
IHC Recommend dilution: |
30-150 |