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英文名称： SOCS2 Antigen (Recombinant Protein)
别 名： CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
|
Fusion protein corresponding to a region derived from 31-198 amino acids of human SOCS2 |
技术规格
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Full name: |
suppressor of cytokine signaling 2 |
|
Synonyms: |
CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2 |
|
Swissprot: |
O14508 |
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Gene Accession: |
BC010399 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. |
