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Background: |
The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus. Alternatively spliced transcript variants encoding different isoforms have been described. |
Applications: |
ELISA, IHC |
Name of antibody: |
VSX1 |
Immunogen: |
Fusion protein of human VSX1 |
Full name: |
visual system homeobox 1 |
Synonyms: |
PPD; KTCN; PPCD; RINX; KTCN1; PPCD1; CAASDS |
SwissProt: |
Q9NZR4 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human lung cancer and human gastric cancer |
IHC Recommend dilution: |
25-100 |