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英文名称： SOX2 Antigen (Recombinant Protein)
别 名： ANOP3; MCOPS3
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
|
Fusion protein corresponding to C terminal 250 amino acids of human SOX2 |
技术规格
|
Full name: |
SRY (sex determining region Y)-box 2 |
|
Synonyms: |
ANOP3; MCOPS3 |
|
Swissprot: |
P48431 |
|
Gene Accession: |
BC013923 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). |
