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英文名称: SPAG5 Antigen (Recombinant Protein)
别 名: MAP126; DEEPEST; hMAP126
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述
Fusion protein corresponding to a region derived from 979-1174 amino acids of human SPAG5 |
技术规格
Full name: |
sperm associated antigen 5 |
Synonyms: |
MAP126; DEEPEST; hMAP126 |
Swissprot: |
Q96R06 |
Gene Accession: |
BC000322 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Sperm-associated antigen 5 is a protein that in humans is encoded by the SPAG5 gene. This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. |