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Background:
This gene encodes a phosphoprotein containing six characteristic repeat motifs. The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription. This locus, along with several other neighboring genes, is deleted in Williams-Beuren syndrome. There are many closely related genes and pseudogenes for this gene on chromosome 7. This gene also has pseudogenes on chromosomes 9, 13, and 21. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Applications:
ELISA, WB, IHC
Name of antibody:
GTF2I
Immunogen:
Synthetic peptide of human GTF2I
Full name:
general transcription factor IIi
Synonyms:
WBS; DIWS; SPIN; IB291; BAP135; BTKAP1; TFII-I; WBSCR6; GTFII-I
SwissProt:
P78347
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human thyroid cancer and Human cervical cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
112 kDa
WB Positive control:
HepG2 cells
WB Recommended dilution:
200-1000