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英文名称： ZEB2 Antigen (Recombinant Protein)
别 名： SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
|
Fusion protein corresponding to a region derived from 1084-1214 amino acids of human ZEB2 |
技术规格
|
Full name: |
zinc finger E-box binding homeobox 2 |
|
Synonyms: |
SIP1; SIP-1; ZFHX1B; HSPC082; SMADIP1 |
|
Swissprot: |
O60315 |
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Gene Accession: |
BC127102 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. |
