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英文名称： ABRAXAS1 Antigen (Recombinant Protein)
别 名： abraxas 1, BRCA1 A complex subunit; ABRA1; CCDC98; FAM175A
储 存： 冷冻（-20℃）
相关类别： 抗原
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Fusion protein corresponding to a region derived from 1-73 amino acids of human ABRAXAS1 |
技术规格
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Full name: |
abraxas 1, BRCA1 A complex subunit |
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Synonyms: |
ABRA1; CCDC98; FAM175A |
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Swissprot: |
Q6UWZ7 |
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Gene Accession: |
BC016905 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
