兔抗HBB多克隆抗体

Background:

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Applications:

ELISA, WB, IHC

Name of antibody:

HBB

Immunogen:

Synthetic peptide of human HBB

Full name:

hemoglobin subunit beta

Synonyms:

CD113t-C; beta-globin

SwissProt:

P68871

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

10-50

WB Predicted band size:

16 kDa

WB Positive control:

Mouse liver tissue, Human heart tissue and Human plasma solution lysates

WB Recommended dilution:

200-1000