手机扫码访问本站
微信咨询
英文名称： ARMC8 Antigen (Recombinant Protein)
别 名： armadillo repeat containing 8; GID5; VID28; S863-2; HSPC056
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 186-385 amino acids of human ARMC8 |
技术规格
|
Full name: |
armadillo repeat containing 8 |
|
Synonyms: |
GID5; VID28; S863-2; HSPC056 |
|
Swissprot: |
Q8IUR7 |
|
Gene Accession: |
BC013424 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMC8 (armadillo repeat containing 8), also known as S863-2, is a 673 amino acid protein that contains 14 ARM repeats, suggesting a role in signal transduction events throughout the cell. Six isoforms of ARMC8 are expressed due to alternative splicing events. The gene encoding ARMC8 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. |
