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英文 名称: Anti-STAT2 (phospho-Tyr690) rabbit polyclonal antibody
别 名: P113; ISGF-3; STAT113
相关 类别: 一抗
储 存: 冷冻(-20℃) 避光
宿 主: Rabbit
抗 原: STAT2 (phospho-Tyr690)
反应种属: Human, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications:
WB
Name of antibody:
STAT2 (phospho-Tyr690)
Immunogen:
Synthetic peptide of human STAT2 (phospho-Tyr690)
Full name:
signal transducer and activator of transcription 2, 113kDa (phospho-Tyr690)
Synonyms:
P113; ISGF-3; STAT113
SwissProt:
P52630
WB Predicted band size:
98 kDa
WB Positive control:
Hela cells treated with IFN-α
WB Recommended dilution:
500-1000