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英文名称: KLRC1 Antigen (Recombinant Protein)
别 名: NKG2; NKG2A; CD159A
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to a region derived from 94-233 amino acids of human KLRC1 |
技术规格
Full name: |
killer cell lectin-like receptor subfamily C, member 1 |
Synonyms: |
NKG2; NKG2A; CD159A |
Swissprot: |
P26715 |
Gene Accession: |
BC053840 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. |