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LC12A1抗原(重组蛋白)

品牌:纪宁生物

货号:JN15738

规格: 1mg 100ug

联系方式:021-66980655

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产品详情

中文名称:  LC12A1抗原(重组蛋白)


英文名称: LC12A1 Antigen (Recombinant Protein)


别      名: BSC1; NKCC2


储      存: 冷冻(-20℃)


相关类别: 抗原


概述


Fusion protein corresponding to a region derived from 80-172 amino acids of human SLC12A1


技术规格

Full name:

Solute carrier family 12 (sodium/potassium/chloride transporters), member 1

Synonyms:

BSC1; NKCC2

Swissprot:

Q13621

Gene Accession:

BC040138

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.

友情链接:
elisa试剂盒 elisa检测试剂盒 elisakit 植物elisa试剂盒 CAS号数据库
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