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英文名称： LF11 Antigen (Recombinant Protein)
别 名： FKLF; FKLF1; MODY7; TIEG2; Tieg3
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to C terminal 300 amino acids of human KLF11 |
|
Full name: |
Kruppel-like factor 11 |
|
Synonyms: |
FKLF; FKLF1; MODY7; TIEG2; Tieg3 |
|
Swissprot: |
O14901 |
|
Gene Accession: |
BC063286 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. |
