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英文名称: MAD1L1 Antigen (Recombinant Protein)
别 名: MAD1; PIG9; TP53I9; TXBP181
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to C terminal 300 amino acids of human MAD1L1 |
技术规格
Full name: |
mitotic arrest deficient 1 like 1 |
Synonyms: |
MAD1; PIG9; TP53I9; TXBP181 |
Swissprot: |
Q9Y6D9 |
Gene Accession: |
BC009964 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. |