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英文名称： MAP3K14 Antigen (Recombinant Protein)
别 名： HS, NIK, HSNIK, FTDCR1B
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to C terminal 300 amino acids of human MAP3K14 |
技术规格
|
Full name: |
mitogen-activated protein kinase kinase kinase 14 |
|
Synonyms: |
HS, NIK, HSNIK, FTDCR1B |
|
Swissprot: |
Q99558 |
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Gene Accession: |
BC035576 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. |
