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英文名称： BEX2 Antigen (Recombinant Protein)
别 名： BEX1; DJ79P11.1
储 存： 冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 1-128 amino acids of human BEX2 |
|
Full name: |
brain expressed X-linked 2 |
|
Synonyms: |
BEX1; DJ79P11.1 |
|
Swissprot: |
Q9BXY8 |
|
Gene Accession: |
BC015522 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. |
