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英文名称： EIF2B3 Antigen (Recombinant Protein)
别 名：eukaryotic translation initiation factor 2B subunit gamma; EIF-2B; EIF2Bgamma
储 存： 冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 202-401 amino acids of human EIF2B3 |
|
Full name: |
eukaryotic translation initiation factor 2B subunit gamma |
|
Synonyms: |
EIF-2B; EIF2Bgamma |
|
Swissprot: |
Q9NR50 |
|
Gene Accession: |
BC018728 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
