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英文名称： FARP2 Antigen (Recombinant Protein)
别 名： FIR; FRG; PLEKHC3
储 存： 冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 1-200 amino acids of human FARP2 |
|
Full name: |
FERM, ARH/RhoGEF and pleckstrin domain protein 2 |
|
Synonyms: |
FIR; FRG; PLEKHC3 |
|
Swissprot: |
O94887 |
|
Gene Accession: |
BC021301 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity). |
