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英文名称： GMDS Antigen (Recombinant Protein)
别 名： GMD; SDR3E1
储 存： 冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 173-372 amino acids of human GMDS |
|
Full name: |
GDP-mannose 4,6-dehydratase |
|
Synonyms: |
GMD; SDR3E1 |
|
Swissprot: |
O60547 |
|
Gene Accession: |
BC000117 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020). |
