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英文名称： LPXN Antigen (Recombinant Protein)
别 名： leupaxin; LDPL
储 存：冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 187-386 amino acids of human LPXN |
|
Full name: |
leupaxin |
|
Synonyms: |
LDPL |
|
Swissprot: |
O60711 |
|
Gene Accession: |
BC019035 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
