兔抗RRAD多克隆抗体

Background:

The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.

Applications:

ELISA, IHC

Name of antibody:

RRAD

Immunogen:

Synthetic peptide of human RRAD

Full name:

Ras-related associated with diabetes

Synonyms：

RAD; RAD1; REM3

SwissProt:

P55042

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human brain and Human ovarian cancer

IHC Recommend dilution:

25-100