兔抗TRIM25多克隆抗体

Background:

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Applications:

ELISA, IHC

Name of antibody:

TRIM25

Immunogen:

Synthetic peptide of human TRIM25

Full name:

tripartite motif containing 25

Synonyms：

EFP; Z147; RNF147; ZNF147

SwissProt:

Q14258

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human liver cancer and Human ovarian cancer

IHC Recommend dilution:

10-50