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英文名称： PPM1G Antigen (Recombinant Protein)
别 名： protein phosphatase, Mg2+/Mn2+ dependent 1G; PP2CG; PPP2CG; PP2CGAMMA
储 存： 冷冻（-20℃）
相关类别： 抗原
概述：
|
Fusion protein corresponding to a region derived from 347-546 amino acids of human PPM1G |
|
Full name: |
protein phosphatase, Mg2+/Mn2+ dependent 1G |
|
Synonyms: |
PP2CG; PPP2CG; PP2CGAMMA |
|
Swissprot: |
O15355 |
|
Gene Accession: |
BC000057 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. |
