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英文名称: RBFOX2 Antigen (Recombinant Protein)
	
别 名: RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3
	
储 存: 冷冻(-20℃)
	
相关类别: 抗原
	
概述:
| Fusion protein corresponding to a region derived from 191-390 amino acids of human RBFOX2 | 
| Full name: | RNA binding fox-1 homolog 2 | 
| Synonyms: | RTA; fxh; FOX2; RBM9; Fox-2; HNRBP2; HRNBP2; dJ106I20.3 | 
| Swissprot: | O43251 | 
| Gene Accession: | BC013115 | 
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE | 
| Expression system: | Escherichia coli | 
| Tags: | His tag C-Terminus, GST tag N-Terminus | 
| Background: | This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene. |