兔抗SIAH1多克隆抗体

Background:

This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]

Applications:

ELISA, WB, IHC

Name of antibody:

SIAH1

Immunogen:

Fusion protein of human SIAH1

Full name:

siah E3 ubiquitin protein ligase 1

Synonyms:

SIAH1A

SwissProt:

Q8IUQ4

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer and Human prostate cancer

IHC Recommend dilution:

250-500

WB Predicted band size:

31 kDa

WB Positive control:

Mouse kidney tissue lysate

WB Recommended dilution:

500-2000