SNAP25抗原（重组蛋白）

Background:

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene.

Tags:

His tag C-Terminus, GST tag N-Terminus

Expression system:

Escherichia coli

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Gene Accession:

BC010647

Swissprot:

P60880

Synonyms:

RIC4; SEC9; SNAP; RIC-4; SNAP-25; bA416N4.2; dJ1068F16.2

Full name:

Synaptosomal-associated protein, 25kDa