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技术规格
Background:
The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis.
Applications:
ELISA, IHC
Name of antibody:
SLC10A1
Immunogen:
Synthetic peptide of human SLC10A1
Full name:
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
Synonyms:
NTCP
SwissProt:
Q14973
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human lung cancer
IHC Recommend dilution:
15-50