TSEN2抗原（重组蛋白）

Full name:

tRNA splicing endonuclease subunit 2

Synonyms:

SEN2; PCH2B; SEN2L

Swissprot:

Q8NCE0

Gene Accession:

BC004178

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.