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英文名称: CD86 Antigen (Recombinant Protein)
别 名: CD86 molecule; B70; B7-2; B7.2; LAB72; CD28LG2
储 存: 冷冻(-20℃)
相关类别 抗原
概述
Fusion protein corresponding to a region derived from 24-329 amino acids of human CD86 |
Full name: |
CD86 molecule |
Synonyms: |
B70; B7-2; B7.2; LAB72; CD28LG2 |
Swissprot: |
P42081 |
Gene Accession: |
BC040261 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. |