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英文名称： DHCR24 Antigen (Recombinant Protein)
别 名： 24-dehydrocholesterol reductase; DCE; SELADIN1; Nbla03646; seladin-1
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to C terminal 217 amino acids of human DHCR24 |
|
Full name: |
24-dehydrocholesterol reductase |
|
Synonyms: |
DCE; SELADIN1; Nbla03646; seladin-1 |
|
Swissprot: |
Q15392 |
|
Gene Accession: |
BC004375 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. |
