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英文名称： RIOX2 Antigen (Recombinant Protein)
别 名： ribosomal oxygenase 2; ROX; MDIG; MINA; NO52; JMJD10; MINA53
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 266-465 amino acids of human RIOX2 |
|
Full name: |
ribosomal oxygenase 2 |
|
Synonyms: |
ROX; MDIG; MINA; NO52; JMJD10; MINA53 |
|
Swissprot: |
Q8IUF8 |
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Gene Accession: |
BC014928 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
