手机扫码访问本站
微信咨询
英文名称： RNF14 Antigen (Recombinant Protein)
别 名： ring finger protein 14; ARA54; HFB30; TRIAD2; HRIHFB2038
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 11-137 amino acids of human RNF14 |
|
Full name: |
ring finger protein 14 |
|
Synonyms: |
ARA54; HFB30; TRIAD2; HRIHFB2038 |
|
Swissprot: |
Q9UBS8 |
|
Gene Accession: |
BC126185 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. |
