手机扫码访问本站
微信咨询
英文名称： SF3A3 Antigen (Recombinant Protein)
别 名： splicing factor 3a subunit 3; PRP9; PRPF9; SAP61; SF3a60
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 302-501 amino acids of human SF3A3 |
|
Full name: |
splicing factor 3a subunit 3 |
|
Synonyms: |
PRP9; PRPF9; SAP61; SF3a60 |
|
Swissprot: |
Q12874 |
|
Gene Accession: |
BC002395 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. |
