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英文名称： SMARCB1 Antigen (Recombinant Protein)
别 名： SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; RDT; INI1; SNF5; Snr1; BAF47;
MRD
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to N terminal 376 amino acids of human SMARCB1 |
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Full name: |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 |
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Synonyms: |
RDT; INI1; SNF5; Snr1; BAF47; MRD15; RTPS1; Sfh1p; hSNFS; SNF5L1; SWNTS1; PPP1R144 |
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Swissprot: |
Q12824 |
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Gene Accession: |
BC117114 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Two transcript variants encoding different isoforms have been found for this gene. |
