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英文名称： SRPX Antigen (Recombinant Protein)
别 名： sushi-repeat containing protein, X-linked; DRS; ETX1; SRPX1; HEL-S-83p
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to C terminal 250 amino acids of human SRPX |
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Full name: |
sushi-repeat containing protein, X-linked |
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Synonyms: |
DRS; ETX1; SRPX1; HEL-S-83p |
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Swissprot: |
P78539 |
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Gene Accession: |
BC020684 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
SRPX gene also designated ETX1, resides within this region and is deleted in XLRP patients. There are at least two splice variants of SRPX, one of which contains a thirty amino acid signal peptide. Both variants contain three complement control protein domains, a hydrophobic region for membrane anchorage, and a cytoplasmic carboxy terminus. SRPX is expressed in retina and heart. SRPX is highly homologous to the drs (downregulated by v-src) human homolog, which suggests a role for SRPX as a tumor suppressor. |
