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英文名称： SWAP70 Antigen (Recombinant Protein)
别 名： SWAP switching B-cell complex 70kDa subunit; HSPC321; SWAP-70
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to C terminal 200 amino acids of human SWAP70 |
|
Full name: |
SWAP switching B-cell complex 70kDa subunit |
|
Synonyms: |
HSPC321; SWAP-70 |
|
Swissprot: |
Q9UH65 |
|
Gene Accession: |
BC000616 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background:
|
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity). |
