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英文名称: TALDO1 Antigen (Recombinant Protein)
别 名: transaldolase 1; TAL; TALH; TAL-H; TALDOR
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to N terminal 170 amino acids of human TALDO1 |
Full name: |
transaldolase 1 |
Synonyms: |
TAL; TALH; TAL-H; TALDOR |
Swissprot: |
P37837 |
Gene Accession: |
BC010103 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. |