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英文名称： THOP1 Antigen (Recombinant Protein)
别 名： thimet oligopeptidase 1; TOP; MP78; EP24.15; MEPD_HUMAN
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 490-689 amino acids of human THOP1 |
|
Full name: |
thimet oligopeptidase 1 |
|
Synonyms: |
TOP; MP78; EP24.15; MEPD_HUMAN |
|
Swissprot: |
P52888 |
|
Gene Accession: |
BC013878 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. |
