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英文名称：TLE1 Antigen (Recombinant Protein)
别 名： transducin like enhancer of split 1; ESG; ESG1; GRG1
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 571-770 amino acids of human TLE1 |
|
Full name: |
transducin like enhancer of split 1 |
|
Synonyms: |
ESG; ESG1; GRG1 |
|
Swissprot: |
Q04724 |
|
Gene Accession: |
BC015747 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. |
