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英文名称： TMPRSS2 Antigen (Recombinant Protein)
别 名： transmembrane protease, serine 2; PP9284; PRSS10
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to a region derived from 106-256 amino acids of human TMPRSS2 |
|
Full name: |
transmembrane protease, serine 2 |
|
Synonyms: |
PP9284; PRSS10 |
|
Swissprot: |
O15393 |
|
Gene Accession: |
BC051839 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. |
