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英文名称: Anti-SNCA rabbit polyclonal antibody
别 名: PD1; NACP; PARK1; PARK4
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: SNCA
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.
Applications:
ELISA, IHC
Name of antibody:
SNCA
Immunogen:
Synthetic peptide of human SNCA
Full name:
synuclein, alpha (non A4 component of amyloid precursor)
Synonyms:
PD1; NACP; PARK1; PARK4
SwissProt:
P37840
ELISA Recommended dilution:
1000-2000
IHC positive control:
Human brain and Human thyroid cancer
IHC Recommend dilution:
25-100