兔抗SLC6A4多克隆抗体

Background:

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Applications:

ELISA, IHC

Name of antibody:

SLC6A4

Immunogen:

Synthetic peptide of human SLC6A4

Full name:

solute carrier family 6 (neurotransmitter transporter), member 4

Synonyms：

HTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR

SwissProt:

P31645

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

50-200