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英文名称： UACA Antigen (Recombinant Protein)
别 名： uveal autoantigen with coiled-coil domains and ankyrin repeats; NUCLING
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
Fusion protein corresponding to C terminal 200 amino acids of human UACA |
|
Full name: |
uveal autoantigen with coiled-coil domains and ankyrin repeats |
|
Synonyms: |
NUCLING |
|
Swissprot: |
Q9BZF9 |
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Gene Accession: |
BC113407 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity). |
