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英文名称： UBE2R2 Antigen (Recombinant Protein)
别 名： ubiquitin conjugating enzyme E2 R2; UBC3B; CDC34B; E2-CDC34B
相关类别： 抗原
储 存： 冷冻（-20℃）
概述
|
Fusion protein corresponding to a region derived from 1-238 amino acids of human UBE2R2 |
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Full name: |
ubiquitin conjugating enzyme E2 R2 |
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Synonyms: |
UBC3B; CDC34B; E2-CDC34B |
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Swissprot: |
Q712K3 |
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Gene Accession: |
BC004862 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. |
