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英文名称: UGT2B4 Antigen (Recombinant Protein)
别 名: UDP glucuronosyltransferase 2 family, polypeptide B4; HLUG25; UDPGTH1; UGT2B11; UDPGT2B4; UDPGTh-1
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to C terminal 200 amino acids of human UGT2B4 |
Full name: |
UDP glucuronosyltransferase 2 family, polypeptide B4 |
Synonyms: |
HLUG25; UDPGTH1; UGT2B11; UDPGT2B4; UDPGTh-1 |
Swissprot: |
P06133 |
Gene Accession: |
BC026264 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid. |