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英文名称: VPS35 Antigen (Recombinant Protein)
储 存: 冷冻(-20℃)
别 名: VPS35 retromer complex component; MEM3; PARK17
相关类别: 抗原
概述
Fusion protein corresponding to C terminal 200 amino acids of human VPS35 |
Full name: |
VPS35 retromer complex component |
Synonyms: |
MEM3; PARK17 |
Swissprot: |
Q96QK1 |
Gene Accession: |
BC002414 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. |