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英文名称：WDFY3 Antigen (Recombinant Protein)
别 名： WD repeat and FYVE domain containing 3; ALFY; ZFYVE25
相关类别： 抗原
储 存： 冷冻（-20℃）
概述
|
Fusion protein corresponding to a region derived from 3327-3526 amino acids of human WDFY3 |
|
Full name: |
WD repeat and FYVE domain containing 3 |
|
Synonyms: |
ALFY; ZFYVE25 |
|
Swissprot: |
Q8IZQ1 |
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Gene Accession: |
BC015214 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy. |
